The card game version of Humans vs. Mosquitoes was designed by Lien Tran and Clay Ewing. Breeding ground illustrations were created by Julia Rose Smart.
The first version of the card game was created for the Come Out and Play SOMA Arts exhibition in Fall 2012. An updated version was created in June 2014 and was first exhibited at the Meaningful Play conference in October 2014. This June 2014 version is available for purchase on the Game Crafter website at https://www.thegamecrafter.com/games/humans-vs-mosquitoes